Glucose-6-phosphate dehydrogenase deficiency.
نویسندگان
چکیده
Out of 20 patients with viral hepatitis whose glucose-6phosphate dehydrogenase (G-6-PD) levels were normal, 14 had clinical evidence of a mild to moderate degree of haemolysis but in all the patients studied the half life of chromium-51-labelled red cells was shortened. Out of 18 viral hepatitis patients deficient in G-6-PD 17 had clinical evidence of haemolysis, and in eight this was more severe than in the group with normal G-6-PD values. Massive intravascular haemolysis occurred in four, three of whom died. The massive haemolysis was attributed to the presence of additional drug-induced oxidative stress to the G-6-PD-deficient red cells.
منابع مشابه
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ورودعنوان ژورنال:
- Critical reviews in oncology/hematology
دوره 20 1-2 شماره
صفحات -
تاریخ انتشار 1995